Posts Tagged: HEPATITIS

Professor leads World Health Organization survey in Cambodia

Professor leads World Health Organization survey in Cambodia

HU’s Professor Junko Tanaka is leading the first nationwide survey of Hepatitis B and Hepatitis C prevalence in Cambodia. She was asked to carry out the survey on behalf of the World Health Organization (WHO) who hope to eradicate the diseases globally by 2030. With the survey work on the ground almost complete, it is hoped that the first results will be available by the end of the year.   Hep B and Hep C are two of the world’s biggest killers. Infection during childhood of Hep B often results in reoccurring infection – increasing the chance of liver cancer and mortality. Professor Tanaka explains that the single best way… Read more

New model for hepatitis B helps identify potential new therapeutic approach

New model for hepatitis B helps identify potential new therapeutic approach

A promising new avenue for treating hepatitis B has been reported by researchers at Hiroshima University who have developed a new animal model of the disease. About two million people worldwide have been exposed to hepatitis B virus. Liver transplantation is often necessary to save the lives of patients who have severe liver damage that results from acute overreaction of the immune system. To develop therapies against acute hepatitis, an appropriate animal model is necessary. “The number of patients who can receive liver transplantation is limited, so there is an urgent need to develop new treatment options,” said Professor Kazuaki Chayama. Professor Chayama and his research group used mice with… Read more

The new detection method for a key drug resistant hepatitis C virus mutation

The new detection method for a key drug resistant hepatitis C virus mutation

A rapid, sensitive, and accurate method to detect drug resistant hepatitis C virus (HCV) mutants has been developed. Researchers at Hiroshima University established a system to rapidly and accurately measure the presence of HCV Y93H drug resistant mutant strains, and evaluate the proportion of patients harboring this mutation prior to treatment. Even in serum samples with low HCV titers, Y93H drug resistant mutation could be successfully detected in more than half of the samples. This new system for detecting mutant strains may provide important pre-treatment information valuable not only for treatment decisions but also for prediction of disease progression in HCV genotype 1b patients. HCV is a major cause of… Read more