Posts Tagged: surgery

World first: Stem cell treatment for lethal STAT1 gene mutation — shows ‘disappointing’ but promising results

World first: Stem cell treatment for lethal STAT1 gene mutation — shows ‘disappointing’ but promising results

The first ever study assessing how patients with “gain of function” mutation of the STAT1 gene respond to stem cell transplantation has taken place. It involved 15 young patients, from nine different countries, each suffering a range of complications caused by the gene’s mutation. Of these, only six survived a regime of stem cell transplantation – with five completely cured and disease free by the study’s conclusion.   The study was carried out by Dr. Satoshi Okada (Hiroshima University), Professor Jennifer Leiding (University of Florida), Professor Tomohiro Morio (Tokyo Medical and Dental University), and Professor Troy Torgerson  (University of Washington). Dr. Okada, who first discovered the STAT1 gain of function… Read more

Hideki Ohdan, gastroenterology

Hideki Ohdan, gastroenterology

A Conversation with Distinguished Professor Hideki Ohdan Distinguished Professor Hideki Ohdan identifies himself as a “surgeon scientist.” He grew up in Hiroshima city and completed a Medical Degree in 1988 and a PhD degree in 1997, both from Hiroshima University. Now, he leads an active medical practice and research laboratory at Hiroshima University Hospital. His career has focused on removing biological barriers to match organ donors with patients who need organ transplants. This project is driven by the immediate needs of clinical patients, but involves solving a larger scientific mystery: how does the immune system recognize its own body as native cells to ignore and recognize foreign cells as invaders… Read more