Posts Categorized: Archives (2014-2016)

A microbial metabolite of linoleic acid ameliorates intestinal inflammation

A microbial metabolite of linoleic acid ameliorates intestinal inflammation

Inflammatory bowel diseases (IBDs), including Crohn disease and ulcerative colitis, are hard to completely cure. Globally, IBDs affect more than 4 million people, today. However, Professor Soichi Tanabe (Graduate School of Biosphere Science, Hiroshima University) and his collaborators have demonstrated that 10-hydroxy-cis-12-octadecenoic acid (HYA), a gut microbial metabolite of linoleic acid, has a suppressive effect… Read more

HiSIM-SOTB, compact transistor model, selected as international industry standard

HiSIM-SOTB, compact transistor model, selected as international industry standard

A new compact transistor model was developed and the framework for realizing a faster design support process and product development for integrated circuits in the ultra-low voltage category was established. The new compact model, HiSIM-SOTB (Hiroshima University STARC IGFET Model Silicon-on-Thin BOX), was developed by Hiroshima University’s HiSIM Research Center in collaboration with its partners… Read more

What are the mechanisms of zooxanthella expulsion from coral?

What are the mechanisms of zooxanthella expulsion from coral?

Coral bleaching, which often results in the mass mortality of corals and in the collapse of coral reef ecosystems, has become an important issue around the world, with the number of coral reefs decreasing annually. Associate Professor Kazuhiko Koike and Ms. Lisa Fujise of the Graduate School of Biosphere Science at Hiroshima University and their… Read more

International conference on the 4-dimensional organization of the nucleus

International conference on the 4-dimensional organization of the nucleus

‘The 4-D Nucleome 2014’ will be held in Hiroshima, Japan In 1944, Nobel Prize-winning physicist Erwin Schrödinger published a book entitled “What Is Life?” in Ireland. Seventy years later, you might get a hint of the answer by exploring the world of “4D Nucleome” in Japan. The latest advances in understanding the principles behind the… Read more

A novel technique for gene insertion by genome editing

A novel technique for gene insertion by genome editing

Easy, accurate, and highly efficient gene knock-in in a variety of cells and organisms Using a novel gene knock-in technique, effective insertion of an exogenous gene was demonstrated in human cells and in animal models, including silkworms and frogs. This strategy universally enables gene knock-in not only in cultured cells, but also in various organisms…. Read more

Establishment of induced pluripotent stem cells from Werner syndrome fibroblasts

Establishment of induced pluripotent stem cells from Werner syndrome fibroblasts

Milestone for understanding diseases and for the development of new therapies Associate Professor Akira Shimamoto and Professor Hidetoshi Tahara at the Graduate School of Biomedical & Health Science in Hiroshima University, Professor Koutaro Yokote at the Graduate School of Medicine in Chiba University, Visiting Professor Makoto Goto at the Medical Center East in Tokyo Women’s… Read more