Posts Tagged: biology

Transcription factor helps tumors grow in low oxygen, resist anticancer therapies

Transcription factor helps tumors grow in low oxygen, resist anticancer therapies

  An international team of researchers found how cancer cells respond to DNA damage signaling when in low oxygen, or hypoxia. Through comprehensive gene expression analyses, the team determined how one family of genes controls DNA damage response, as well as how it weakens the effectiveness of anticancer therapies. Our bodies have strict molecular mechanisms… Read more

Highly safe biocontainment strategy hopes to encourage greater use of GMOs

Highly safe biocontainment strategy hopes to encourage greater use of GMOs

Hiroshima University researchers believe their simple phosphite-based control method will convince legislators to get with the times Use of genetically modified organisms (GMOs) – microorganisms not found in the natural world but developed in labs for their beneficial characteristics – is a contentious issue. For while GMOs could greatly improve society in numerous ways –… Read more

“Smart” genetic library – making disease diagnosis much easier

“Smart” genetic library – making disease diagnosis much easier

Hiroshima University finds way to determine disease-causing mutations Researchers at Hiroshima University have developed a smart genetic reference library for locating and weeding out disease-causing mutations in populations. The technique and database, developed by Dr. Satoshi Okada, of HU’s Graduate School of Biomedical & Health Sciences, has successfully estimated naturally occurring rare-variants in the STAT1… Read more

Kazunori Imaizumi, biochemistry

Kazunori Imaizumi, biochemistry

A Conversation with Distinguished Professor Kazunori Imaizumi A Common Cause Inside the cells of animals and plants is a folded, flattened tube of membranes piled on top of themselves. Studded along portions of the inside of this tube are ribosomes, small organelles that turn messages from DNA into protein. The proteins and occasionally important fats,… Read more

How females store sperm: fertility study in chickens examines fatty acids

How females store sperm: fertility study in chickens examines fatty acids

The science of breeding chickens has revealed part of the mystery of how certain female animals are able to store sperm long-term.  Droplets of fat transferred from female cells to sperm cells may contribute to keeping sperm alive. Females of some types of insects, reptiles, and birds can store sperm from multiple males within specialized… Read more

Active deformations of cell nuclei contribute to intra-nuclear architecture formations

Active deformations of cell nuclei contribute to intra-nuclear architecture formations

There are two types of chromatin, euchromatin and heterochromatin, that vary with the stages of the cell cycle. In particular, euchromatin with rich active genes localizes to the interior of the nucleus during interphase; heterochromatin usually localizes to the periphery of the nucleus. Akinori Awazu, an Associate Professor at the Research Center for Mathematics on… Read more