Posts Tagged: cellular biology

New target for chronic pain relief confirmed by scientists

New target for chronic pain relief confirmed by scientists

Scientists observe drug target that can reduce pain when activated   A research group at Hiroshima University observed a potential new target for chronic pain treatment. Further research using this receptor could lead to new, more effective drugs to use in pain-relieving treatment for chronic pain. Conditions that cause chronic pain can be difficult to manage. These… Read more

Space-like gravity weakens muscle development

Space-like gravity weakens muscle development

Microgravity conditions affect DNA methylation of muscle cells, slowing their differentiation   Astronauts go through many physiological changes during their time in spaceflight, including lower muscle mass and slower muscle development. Similar symptoms can occur in the muscles of people on Earth’s surface, too. In fact, it could affect everyone to some extent later in… Read more

Transcription factor helps tumors grow in low oxygen, resist anticancer therapies

Transcription factor helps tumors grow in low oxygen, resist anticancer therapies

  An international team of researchers found how cancer cells respond to DNA damage signaling when in low oxygen, or hypoxia. Through comprehensive gene expression analyses, the team determined how one family of genes controls DNA damage response, as well as how it weakens the effectiveness of anticancer therapies. Our bodies have strict molecular mechanisms… Read more

Highly safe biocontainment strategy hopes to encourage greater use of GMOs

Highly safe biocontainment strategy hopes to encourage greater use of GMOs

Hiroshima University researchers believe their simple phosphite-based control method will convince legislators to get with the times Use of genetically modified organisms (GMOs) – microorganisms not found in the natural world but developed in labs for their beneficial characteristics – is a contentious issue. For while GMOs could greatly improve society in numerous ways –… Read more

Kazunori Imaizumi, biochemistry

Kazunori Imaizumi, biochemistry

A Conversation with Distinguished Professor Kazunori Imaizumi A Common Cause Inside the cells of animals and plants is a folded, flattened tube of membranes piled on top of themselves. Studded along portions of the inside of this tube are ribosomes, small organelles that turn messages from DNA into protein. The proteins and occasionally important fats,… Read more

Active deformations of cell nuclei contribute to intra-nuclear architecture formations

Active deformations of cell nuclei contribute to intra-nuclear architecture formations

There are two types of chromatin, euchromatin and heterochromatin, that vary with the stages of the cell cycle. In particular, euchromatin with rich active genes localizes to the interior of the nucleus during interphase; heterochromatin usually localizes to the periphery of the nucleus. Akinori Awazu, an Associate Professor at the Research Center for Mathematics on… Read more