Posts Tagged: Distinguished Professors

Shigeto Yamawaki, psychology

Shigeto Yamawaki, psychology

A Conversation with Distinguished Professor Shigeto Yamawaki Excitement in a Black Box “The brain used to be a black box. You cannot approach the brain directly, like you can simply biopsy a tumor to study cancer.” Distinguished Professor Shigeto Yamawaki has opened up that black box over the course of his 27-year career at Hiroshima University, making important strides in advancing medical understanding of the human brain. Yamawaki leads a research project called “Center of KANSEI Innovation: Nurturing Mental Welfare”, working in collaboration with a Japanese car company and many other research institutes and manufacturing companies. The project team’s ultimate goal is to create a happy society that nurtures mental welfare,… Read more

Power up when the temperature is down

Power up when the temperature is down

Transporting power sources in the coldest places may be easier with a new re-chargeable, non-metallic battery from Japan. This “eco battery” could provide portable sources of power in environments like refrigerated factories or extreme winter environments. Chemists from Hiroshima University developed a new synthesis method for organic radical batteries that are re-chargeable and continue to function at below-freezing temperatures.  The specific model prototyped by the Hiroshima University team has greater voltage than previously reported styles from other research groups around the world.  The method used to create this battery is an improvement on a report from the same Hiroshima University laboratory earlier in 2016. Most electrical devices use a lithium-ion… Read more

Pathway to better metabolism discovered in fat cells

Pathway to better metabolism discovered in fat cells

Control over obesity and diabetes may be one step closer thanks to a Hiroshima University study in fat tissue. The research team of Professor Kazunori Imaizumi, PhD, at Hiroshima University has mapped the activation pathway for a protein responsible for burning excess energy in the body. If the pathway can be confirmed in living animal studies, control of this pathway may lead to treatments for obesity and related metabolic diseases.  Researchers studied mouse fat cells growing in a dish using a combination of chemical treatments and protein measurements. Part of the pathway involves a protein found only in brown fat cells.  Fat cells are classified as either brown or white.  White… Read more

New genetic cause of gastric and prostate cancer identified

New genetic cause of gastric and prostate cancer identified

Researchers at Hiroshima University have opened the door to finding a new class of cancer-causing genetic variations. Using a combination of pre-existing electronic databases and their own experiments with cancerous and healthy cells, researchers linked stomach (gastric) and prostate cancer to a specific type of DNA called transcribed-ultraconserved regions (T-UCRs).  This approach will likely reveal more links between T-UCRs and other cancers in the future. Modern research studies, like this one led by Professor Wataru Yasui, the Dean of the Institute and Graduate School of Biomedical & Health Sciences at Hiroshima University, are enhancing traditional understandings of cancer genetics. The human genome is made of lots of DNA, but only… Read more

New model for hepatitis B helps identify potential new therapeutic approach

New model for hepatitis B helps identify potential new therapeutic approach

A promising new avenue for treating hepatitis B has been reported by researchers at Hiroshima University who have developed a new animal model of the disease. About two million people worldwide have been exposed to hepatitis B virus. Liver transplantation is often necessary to save the lives of patients who have severe liver damage that results from acute overreaction of the immune system. To develop therapies against acute hepatitis, an appropriate animal model is necessary. “The number of patients who can receive liver transplantation is limited, so there is an urgent need to develop new treatment options,” said Professor Kazuaki Chayama. Professor Chayama and his research group used mice with… Read more

The new detection method for a key drug resistant hepatitis C virus mutation

The new detection method for a key drug resistant hepatitis C virus mutation

A rapid, sensitive, and accurate method to detect drug resistant hepatitis C virus (HCV) mutants has been developed. Researchers at Hiroshima University established a system to rapidly and accurately measure the presence of HCV Y93H drug resistant mutant strains, and evaluate the proportion of patients harboring this mutation prior to treatment. Even in serum samples with low HCV titers, Y93H drug resistant mutation could be successfully detected in more than half of the samples. This new system for detecting mutant strains may provide important pre-treatment information valuable not only for treatment decisions but also for prediction of disease progression in HCV genotype 1b patients. HCV is a major cause of… Read more