Posts Tagged: medicine

Transcription factor helps tumors grow in low oxygen, resist anticancer therapies

Transcription factor helps tumors grow in low oxygen, resist anticancer therapies

  An international team of researchers found how cancer cells respond to DNA damage signaling when in low oxygen, or hypoxia. Through comprehensive gene expression analyses, the team determined how one family of genes controls DNA damage response, as well as how it weakens the effectiveness of anticancer therapies. Our bodies have strict molecular mechanisms… Read more

World first: Stem cell treatment for lethal STAT1 gene mutation — shows ‘disappointing’ but promising results

World first: Stem cell treatment for lethal STAT1 gene mutation — shows ‘disappointing’ but promising results

The first ever study assessing how patients with “gain of function” mutation of the STAT1 gene respond to stem cell transplantation has taken place. It involved 15 young patients, from nine different countries, each suffering a range of complications caused by the gene’s mutation. Of these, only six survived a regime of stem cell transplantation… Read more

Scientists aim to reduce animals killed in drug testing

Scientists aim to reduce animals killed in drug testing

That’s the hope of Associate Professor Noriyuki Yanaka and researchers at Hiroshima University who have developed a non-invasive way to assess the anti-inflammatory properties of fortified health foods and medications. The team from HU’s Graduate School of Biosphere Science believe their technique for examining fatty tissues will greatly reduce the numbers of lab mice sacrificed… Read more

Lasers, key to unlocking memory

Lasers, key to unlocking memory

New method uses near infrared light to shed light on memory loss conditions Researchers at Hiroshima University have developed a new laser activated technique for bridging missing links in memory flow. The brainchild of Professor Manabu Abe of Hiroshima Universities Department of Chemistry, it aims to open up the mysterious world of neurotransmission – increasing… Read more

“Smart” genetic library – making disease diagnosis much easier

“Smart” genetic library – making disease diagnosis much easier

Hiroshima University finds way to determine disease-causing mutations Researchers at Hiroshima University have developed a smart genetic reference library for locating and weeding out disease-causing mutations in populations. The technique and database, developed by Dr. Satoshi Okada, of HU’s Graduate School of Biomedical & Health Sciences, has successfully estimated naturally occurring rare-variants in the STAT1… Read more

Hideki Ohdan, gastroenterology

Hideki Ohdan, gastroenterology

A Conversation with Distinguished Professor Hideki Ohdan Distinguished Professor Hideki Ohdan identifies himself as a “surgeon scientist.” He grew up in Hiroshima city and completed a Medical Degree in 1988 and a PhD degree in 1997, both from Hiroshima University. Now, he leads an active medical practice and research laboratory at Hiroshima University Hospital. His… Read more