Posts Tagged: Physiology

Vest helps athletes keep their cool

Vest helps athletes keep their cool

A new cooling vest for sports athletes may ensure everyone can compete safely in sweltering summer conditions such as the upcoming 2020 Summer Olympics, reports a new paper published in Frontiers in Physiology. Strategies to cope with body heat in sports is a pressing issue. The Tokyo Olympics will be held in the hot and muggy Japanese summer where the ambient temperature is expected to be above 33°C. Athletes have to worry about performing under pressure of the high-stakes competition but also now have to deal with a very hot and humid climate. The 2022 FIFA World Cup in Qatar will also have high temperatures and athletes must use cooling… Read more

Family dynamics: molecules from the same family have different effects in cancer prognosis

Family dynamics: molecules from the same family have different effects in cancer prognosis

Scientists observe that one molecule increases liposarcoma tumor cell spread and aggression while another molecule from the same family decreases migration and cell proliferation. Researchers at Hiroshima University have found that different levels of two molecules of the same family—TIMP-1 and TIMP-4—can influence prognosis of liposarcoma. High levels of TIMP-1 lead to a poor prognosis while high TIMP-4 indicates a less severe form of liposarcoma. This study, published in Carcinogenesis 10th May, described the molecules’ mechanism of action through the YAP/TAZ pathway. Further research can lead to new treatments and better methods of diagnosis for liposarcoma. Different types of cancer have different prognoses (medical outcomes) and some are easier to… Read more

This oral appliance could help you (and your partner) sleep better

This oral appliance could help you (and your partner) sleep better

An original design for an oral appliance developed in Hiroshima University Hospital can help sufferers of sleep apnea sleep more soundly   Researchers measured a novel treatment for sleep apnea developed at Hiroshima University Hospital with positive results. By measuring patients lying down flat, the researchers stimulated sleep conditions and measured the patient’s airways using 3D imaging. The study confirmed that the treatment is effective at opening the airways and warrants further collaboration between dentists and doctors in treatment of sleep apnea. Obstructive sleep apnea is a condition that causes throat muscles to relax and narrows the airways of those affected while they are asleep. Snorting, choking or gasping while… Read more

New target for chronic pain relief confirmed by scientists

New target for chronic pain relief confirmed by scientists

Scientists observe drug target that can reduce pain when activated   A research group at Hiroshima University observed a potential new target for chronic pain treatment. Further research using this receptor could lead to new, more effective drugs to use in pain-relieving treatment for chronic pain. Conditions that cause chronic pain can be difficult to manage. These include sciatica, cancer and rheumatoid arthritis. Chronic pain mechanisms are complicated, which is one of the reasons why pain management is so difficult, explains Professor Norimitsu Morioka of the Department of Pharmacology, Graduate School of Biomedical & Health Sciences, Hiroshima University. This difficulty decreases the quality of life of patients that, in many cases, can suffer from… Read more