Posts Tagged: Research Institute for Radiation Biology and Medicine

Meet Akiko Kubota

Meet Akiko Kubota

  In the summer of 2015, when she moved from Tokyo to Hiroshima, Akiko Kubota was surprised by two things: One, the love and excitement towards the Hiroshima Carp baseball team; and two, the fraught relationship concerning the atomic bomb and the people of Hiroshima. August 6, 2018, marks the 73rd anniversary of the day… Read more

Transcription factor helps tumors grow in low oxygen, resist anticancer therapies

Transcription factor helps tumors grow in low oxygen, resist anticancer therapies

  An international team of researchers found how cancer cells respond to DNA damage signaling when in low oxygen, or hypoxia. Through comprehensive gene expression analyses, the team determined how one family of genes controls DNA damage response, as well as how it weakens the effectiveness of anticancer therapies. Our bodies have strict molecular mechanisms… Read more

A genetic polymorphism associated with lung cancer progression

A genetic polymorphism associated with lung cancer progression

Genetic polymorphisms associated with cancer progression lead to variations in gene expression and may serve as prognostic markers for lung cancer. Researchers at the Hiroshima University and Saitama Medical University found that in patients with lung cancer, a single nucleotide polymorphism (SNP) may regulate gene and protein expression and be associated with poor prognosis. To… Read more

How do harmful chronic myelogenous leukemia stem cells obtain their nutrients?

How do harmful chronic myelogenous leukemia stem cells obtain their nutrients?

Applicability of a new strategy to overcome disease recurrence in patients with chronic myelogenous leukemia     A research group in Japan and in Korea has found a novel nutrient uptake process that maintains the activity of murine chronic myelogenous leukemia (CML) stem cells. Pharmacological inhibition of nutrient uptake decreased CML stem cell activity in… Read more